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Nathalie Lapointe Selected Research

omapatrilat

10/2005Vasopeptidase inhibition peri- and post-MI in Zucker insulin resistant rats: effect on MI size, arrhythmias, remodeling, function and fetal gene expression.
3/2005Effects of the vasopeptidase inhibitor omapatrilat on peri- and postmyocardial infarction in Zucker lean rats.
12/2003Comparative effects of a vasopeptidase inhibitor vs. an angiotensin converting enzyme inhibitor on cardiomyocyte apoptosis in rats with heart failure.
7/2003Effects of pre-, peri-, and postmyocardial infarction treatment with omapatrilat in rats: survival, arrhythmias, ventricular function, and remodeling.
5/2002Comparison of the effects of an angiotensin-converting enzyme inhibitor and a vasopeptidase inhibitor after myocardial infarction in the rat.
1/2002Effects of captopril and omapatrilat on early post-myocardial infarction survival and cardiac hemodynamics in rats: interaction with cardiac cytokine expression.

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Nathalie Lapointe Research Topics

Disease

6Myocardial Infarction
11/2005 - 01/2002
5Infarction (Infarctions)
10/2009 - 05/2002
4Heart Failure
12/2003 - 03/2002
3Cardiomegaly (Heart Hypertrophy)
03/2010 - 03/2005
3Hypertrophy
11/2006 - 05/2002
3Insulin Resistance
10/2005 - 04/2003
3Fibrosis (Cirrhosis)
12/2003 - 05/2002
2Cicatrix (Scar)
12/2003 - 05/2002
1Inflammation (Inflammations)
03/2010
1Albuminuria
11/2006
1Diabetes Mellitus
11/2006
1Hypertension (High Blood Pressure)
11/2005
1Right Ventricular Hypertrophy
03/2005
1Cardiac Arrhythmias (Arrythmia)
07/2003
1Type 2 Diabetes Mellitus (MODY)
04/2003
1Isolated Systolic Hypertension
05/2002
1Ventricular Remodeling
05/2002
1Cardiovascular Diseases (Cardiovascular Disease)
04/2002

Drug/Important Bio-Agent (IBA)

6omapatrilatIBA
10/2005 - 01/2002
6Vasopeptidase InhibitorsIBA
10/2005 - 01/2002
4Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
12/2003 - 01/2002
3Losartan (Cozaar)FDA LinkGeneric
11/2005 - 04/2003
3Captopril (Capoten)FDA LinkGeneric
12/2003 - 01/2002
2Messenger RNA (mRNA)IBA
11/2006 - 01/2002
2Insulin (Novolin)FDA Link
11/2005 - 10/2005
2Angiotensin Receptor AntagonistsIBA
11/2005 - 04/2005
2CytokinesIBA
05/2002 - 01/2002
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
03/2002 - 01/2002
1NG-Nitroarginine Methyl Ester (L-NAME)IBA
03/2010
1Plasminogen Activators (Plasminogen Activator)IBA
03/2010
1NestinIBA
10/2009
1Transforming Growth Factor beta (TGF-beta)IBA
11/2006
1Mineralocorticoid Receptor AntagonistsIBA
11/2006
1Proteins (Proteins, Gene)FDA Link
11/2006
1Streptozocin (Streptozotocin)FDA Link
11/2006
1Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
11/2006
1OsteopontinIBA
11/2006
1Endothelin Receptors (Endothelin Receptor)IBA
10/2003
1Endothelins (Endothelin)IBA
10/2003
1Endothelin Receptor AntagonistsIBA
10/2003
1Ramipril (Altace)FDA LinkGeneric
04/2003
1BradykininIBA
04/2003
1AntioxidantsIBA
05/2002
1Probucol (Lorelco)FDA Link
05/2002
1Vasodilator Agents (Vasodilators)IBA
04/2002
1Vasoconstrictor AgentsIBA
04/2002
1Neprilysin (Neutral Endopeptidase)IBA
01/2002

Therapy/Procedure

1Ligation
05/2002